Increased Mitochondrial Oxidative Phosphorylation in the Liver Is Associated With Obesity and Insulin Resistance
نویسندگان
چکیده
منابع مشابه
Mitochondrial Deficiency Is Associated With Insulin Resistance
The specific cellular underpinnings or mechanisms of insulin resistance (IR) are not clear. Here I present evidence to support a causal association between mitochondrial energetics and IR. A large body of literature indicates that mitochondrial capacity for oxidative metabolism is lower in human obesity and type 2 diabetes. Whether or not mitochondria play a causal role in IR is hotly debated. ...
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ژورنال
عنوان ژورنال: Obesity
سال: 2011
ISSN: 1930-7381
DOI: 10.1038/oby.2010.214